Education:

Selected Recent Publications:

1. [1] C. Guo^#, Z. Wu, H. Xu, Y. Zhou, B. Jiang, D. Lin*, Structural basis of cefotetan up-regulating human RKIP-mediated Ras/Raf1/MEK/ERK signal pathway. Acta Biochimica et Biophysica Sinica, in press (2022). (IF 3.848)

2. [2] C. Guo^#, H. Zhang^#, W. Lin, H. Chen, T. Chang, Z.Wu, J.Yu, D. Lin*, ADP-induced conformational transition of human adenylate kinase 1 is triggered by suppressing internal motion of α3α4 and α7α8 fragments on the ps-ns timescale. Biomolecules, in press (2022). (IF 4.879)

3. [3] W. Shao*, B. Liu, C. Huang, Y. Wu, Z. Zhang, D. Lin*, β-hydroxybutyrate in cardiovascular diseases： a minor metabolite of great expectations. Frontiers in Molecular Biosciences, in press (2022). (IF 5.246)

4. [4] B. Jiang, J. Zhang, G. Zhao, M. Liu, J. Hu, F. Lin, J. Wang, W. Zhao, H. Ma, C. Zhang, C. Wu, L. Yao, Q. Liu, X. Che, Y. Cao, Y. Zheng, C. Zhang, A. Han, D. Lin, Q. Li*, Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis, Molecular Cell, 82(3): 1-15 (2022). (IF 17.970)

5. [5] Z. Wang, D. Guo, Z. Tu, Y. Huang, Y. Zhou, J. Wang, L. Feng, D. Lin, Y. You, T. Agback, V. Orekhov, X. Qu, A Sparse Model-inspired Deep Thresholding Network for Exponential Signal Reconstruction-Application in Fast Biological Spectroscopy, IEEE Transactions on Neural Networks and Learning Systems，10.1109/Tnnls.2022.3144580 (2022). (IF 10.451)

6. [6] Q. Kong^#, J. Gu^#, R. Lu, C. Huang, X. Hu, W. Wu, D. Lin*, NMR-based metabolomic analysis of sera in mouse models of CVB3-induced viral myocarditis and dilated cardiomyopathy, Biomolecules, DOI: 10.3390/biom12010112 (2022). (IF 4.879)

7. [7] P. Cui, X. Li, C. Huang, Q. Li, D. Lin*, Metabolomics and its applications in cancer cachexia Metabolomics and its applications in cancer cachexia, Frontiers in Molecular Biosciences, DOI: 10.3389/fmolb.2022.789889 (2022). (IF 5.246)

8. [8] Y. Zhou^#, F. Lin^#, T. Wan^#, A. Chen^#, H. Wang^#, B. Jiang, W. Zhao, S. Liao, S. Wang, G. Li, Z. Xu, J. Wang, J. Zhang, H. Ma, D. Lin, Q. Li*, ZEBI enhances Warburg effect to facilitate tumorigenesis and metastasis of HCC by transcriptionally activating PFKM, Theranostics, 11 (12): 5926-5938 (2021). (IF 11.556)

9. [9] J. Zhuang, S. Fan, C. Guo, L. Feng, H. Wang, D. Lin*, X. Liao*, Crystal Structure of the Polyketide Cyclase from Mycobacterium tuberculosis, Acta Biochimica et Biophysica Sinica, in press (2021). (IF 3.848)

10. [10] Y. Su, J. Li, W. Zhang, J. Ni, R. Huang, Z. Wang, S. Cheng, Y. Wang, Z. Tian, Q. Zhou, D. Lin, W. Wu, C. Tang, X. Liu, J. Lu, and Y. Yao*, Methylation of PhoP by CheR regulates Salmonella virulence, mBio, DOI:10.1128/mBio.02099-21 (2021). (IF 7.867)

11. [11] T. Jiang^#, Q. Du^#, C. Huang, W. Xu, P. Guo, W. Li, X. Xie, Y. Guo, D. Liu*, D. Lin*, NMR-based metabolomic analysis on the protective effects of apolipoprotein A-I mimetic peptide against contrast media-induced endothelial dysfunction, Molecules, 26：5123 (2021). (IF 4.411)

12. [12] Y. Guo, W. Li, M. Qian, T. Jiang, P. Guo, Q. Du, N. Lin, X. Xie, Z. Wu, D. Lin, D. Liu*, D-4F Ameliorates Contrast Media-Induced Oxidative Injuries in Endothelial Cells via the AMPK/PKC Pathway. Front Pharmacol., 11: 556074(2021). (IF 5.810)

13. [13] L. Zhou, T. Zhang, W. Shao, R. Lu, L. Wang, H. Liu, B. Jiang, S. Li，H. Zhuo，S. Wangle， Q. Li, C. Huang*, D. Lin*, Amiloride ameliorates muscle wasting in cancer cachexia through inhibiting tumor-derived exosome release, Skeletal Muscle, 2021, 11:1-17, DOI：10.1186/s13395-021-00274-5. (IF 4.912)

14. [14] S. Fan, J. Zhuang, C. Guo, D. Lin*, X. Liao*, ¹H, ¹³C, ¹⁵N backbone and side-chain chemical shift assignments of the polyketide cyclase from Mycobacterium Tuberculosis, Biomolecular NMR Assignments, DOI: 10.1007/s12104-021-10036-5 (2021). (IF 0.746)

15. [15] L. Zhou, R, Lu, C. Huang, D. Lin*, Taurine protects C2C12 myoblasts from impaired cell proliferation and myotube differentiation under cisplatin-induced ROS exposure, Frontiers in Molecular Biosciences, 8: 685362. DOI: 10.3389/fmolb.2021.685362 (2021). (IF 5.246)

16. [16] L. Xu, H. Song, Q. Qiu, T. Jiang, P. Ge, Z. Su, W. Ma, R. Zhang, C. Huang, S. Li*, D. Lin*, J. Zhang*, Different expressions of HIF-1α and metabolism in brain and major visceral organs of acute hypoxic mice. International Journal of Molecular Science, 22: 6705, DOI: 10.3390/ijms22136705 (2021) (IF 5.923)

17. [17] T. Song, Y. Guo, Z. Xue, Z. Guo, Z. Wang, D. Lin*, H. Zhang, H. Pan, X. Zhang, F. Yin, H. Wang, L. Uwituze, Z. Zhang*, Small-molecule inhibitor targeting the Hsp70-Bim protein-protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance, Leukemia, 35(10):2862-2874，DOI: 10.1038/s41375-021-01283-5 (2021). (IF 11.528)

18. [18] H. Zhang, Q. Zhou, C. Guo, L. Feng, H. Wang, X. Liao, D. Lin*,
    Structural Basis for the C-terminal Domain of Mycobacterium Tuberculosis Ribosome Maturation Factor RimM to Bind Ribosomal Protein S19,
    Biomolecules, 11(4): 597. DOI: 10.3390/biom11040597 (2021). (IF 4.879)

19. [19] H. Zhang, C. Guo*, D. Lin*, ¹H, ¹³C, ¹⁵N backbone and side-chain NMR assignments of the C-terminal Domain of Mycobacterium Tuberculosis Ribosome Maturation Factor RimM, Biomolecular NMR Assignments, DOI：10.1007/s12104-021-10032-9 (2021). (IF 0.746)

20. [20] Q. Zhang, H. Zhang, F. Zheng, R. Liu, X. Liao, C. Guo*, D. Lin*， ¹H, ¹³C, ¹⁵N backbone and side-chain resonance assignments of the pathogenic G131V mutant of human prion protein (91-231). Biomolecular NMR Assignments, (2021). (IF 0.746)